The Ankle Ailment Known as Cuboid Syndrome

Cuboid syndrome, also known as cuboid subluxation or lateral plantar neuritis, is a relatively rare and painful condition that affects the cuboid bone in the foot. The cuboid bone is a cube-shaped bone located on the outer side of the foot, forming a vital part of the foot's structure and stability. Cuboid syndrome can be caused by various reasons. The cuboid bone can shift out of alignment by rolling or twisting the ankle or it can happen from overuse or repetitive stress. This is a common condition among ballet dancers, as a result of this type of dance style. Having poor foot biomechanics such as flat feet, overpronation, or other foot abnormalities also can disrupt the cuboid's positioning. Wearing shoes that do not fit properly can contribute to developing cuboid syndrome as well. Common symptoms include pain on the lateral side of the foot, difficulty in walking, and discomfort while bearing weight. Early diagnosis and appropriate treatment can aid in resolving cuboid syndrome effectively. If you have pain on the outside of your foot, it is suggested that you consult with a podiatrist for an accurate diagnosis and treatment options. 

Cuboid syndrome, also known as cuboid subluxation, occurs when the joints and ligaments near the cuboid bone in the foot become torn. If you have cuboid syndrome, consult with Frank Henry, DPM from Marble Falls, TX. Our doctor will assess your condition and provide you with quality foot and ankle treatment.

Cuboid syndrome is a common cause of lateral foot pain, which is pain on the outside of the foot. The condition may happen suddenly due to an ankle sprain, or it may develop slowly overtime from repetitive tension through the bone and surrounding structures.


The most common causes of cuboid syndrome include:

  • Injury – The most common cause of this ailment is an ankle sprain.
  • Repetitive Strain – Tension placed through the peroneus longus muscle from repetitive activities such as jumping and running may cause excessive traction on the bone causing it to sublux.
  • Altered Foot Biomechanics – Most people suffering from cuboid subluxation have flat feet.


A common symptom of cuboid syndrome is pain along the outside of the foot which can be felt in the ankle and toes. This pain may create walking difficulties and may cause those with the condition to walk with a limp.


Diagnosis of cuboid syndrome is often difficult, and it is often misdiagnosed. X-rays, MRIs and CT scans often fail to properly show the cuboid subluxation. Although there isn’t a specific test used to diagnose cuboid syndrome, your podiatrist will usually check if pain is felt while pressing firmly on the cuboid bone of your foot.


Just as the range of causes varies widely, so do treatments. Some more common treatments are ice therapy, rest, exercise, taping, and orthotics.

If you have any questions, please feel free to contact our office located in Marble Falls, TX . We offer the newest diagnostic and treatment technologies for all your foot care needs.


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